Effect of Early Amino Acids Supplementation on Serum Glucose and Calcium of Very Low Birth Weight Premature Infants by Ghassan Saleh Ahmed Salama in Progressing Aspects in Pediatrics and Neonatology in Lupine Publishers.
Objective: To examine effects of early amino acid (AA) infusion on serum glucose and calcium levels of very low birth weight
(VLBW) preterm newborns, through the first 72 hours of life.
Study Design: hospital designed prospective study of total 110 VLBW newborns with < 32 weeks gestation, and less than 1500
g was performed. 55 newborns received AA within 6 hours of life (early group) while 55 newborns did not receive AA during the
first 72 hours of life (late group).
Results: Average glucose levels were significantly lower in the early group during the first 72 hours of life. Average serum Ca
levels during first 72 hours of life were significantly higher in newborns with early group.
Conclusions: Early amino acid infusion improve serum glucose and Ca levels in VLBW newborns, and thus decreasing the risk
of hyperglycemia and hypocalcemia among VLBW infants.
Very Low birth weight infants (VLBW) are born at a time when
the fetus is undergoing rapid intrauterine brain and body growth.
Continuation of this growth in the first several weeks postnatally is
often a challenge because these infants are usually highly stressed
and at risk for catabolism. [1] Parenteral nutrition is needed in
these infants because most cannot meet the majority of their
nutritional needs using the enteral route.
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