A Profile of Microbial Isolates and Antibiotic Susceptibility Patterns in Neonatal Sepsis at a Tertiary Care Centre in South India - A Post HOC Analysis by Santosh Kumar Kamalakannan in PAPN - Lupine Publishers
Neonatal sepsis is a clinical syndrome of bacteremia with systemic signs and symptoms of infection in the neonatal period [1,2]. Neonatal sepsis is broadly classified into two types namely early onset sepsis and late onset sepsis. Early onset sepsis is caused by organisms prevalent in the maternal genital tract, labour room or operating theatre, while late onset sepsis usually results from nosocomial or community-acquired infection. Sepsis is one of the major causes of mortality in neonates. According to World Health Organization (WHO) estimates, there are about 5 million neonatal deaths a year, with 98% occurring in developing countries [3]. The incidence of neonatal sepsis according to the data from National Neonatal Perinatal Database (NNPD, 2002-03) is 30 per 1000 live births and contributes to 19% of all neonatal deaths [4]. Neonatal sepsis is caused by a variety of Gram +ve as well as Gram -ve bacteria and rarely by fungus and yeast [5]. Diagnosis of neonatal sepsis clinically is difficult as the symptoms and signs are non-specific- Lupine Publishers.
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